![]() There is overwhelming scientific evidence that vaccination is the best defence against serious infections. The panel recommends whether and how the vaccines should be used. ![]() Once a clinical trial shows that a COVID-19 vaccine is safe and effective, a series of independent reviews of the efficacy and safety evidence is required, including regulatory review and approval in the country where the vaccine is manufactured, before WHO considers a vaccine product for prequalification.Īn external panel of experts convened by WHO analyzes the results from clinical trials, along with evidence on the disease, age groups affected, risk factors for disease, and other information. These trials, which include people at high risk for COVID-19, are specifically designed to identify any common side effects or other safety concerns. Steps taken to ensure the COVID-19 vaccine is safeĬOVID-19 vaccines go through a rigorous, multi-stage testing process, including large trials that involve tens of thousands of people. Officials in individual countries decide whether to approve the vaccines for national use and develop policies for how to use the vaccines in their country based on the WHO recommendations.The panel then recommends whether and how the vaccines should be used. ![]() An external panel of experts convened by WHO, called the Strategic Advisory Group of Experts on Immunization (SAGE), analyzes the results from clinical trials.The evidence must also be reviewed for the purpose of policy recommendations on how the vaccines should be used.A series of independent reviews of the efficacy and safety evidence is required.The vaccines must be proven safe and effective in large clinical trials.Process is followed before a vaccine is given to the publicīefore COVID-19 vaccines can be delivered: Vaccinating not only protects yourself, but also protects those in the community who are unable to be vaccinated. But with herd immunity, these people will have substantial protection, thanks to those around them being vaccinated. This is called herd immunity.īut no single vaccine provides 100% protection, and herd immunity does not provide full protection to those who cannot safely be vaccinated. So the more that others are vaccinated, the less likely people who are unable to be protected by vaccines are at risk of even being exposed to the harmful pathogens. When a lot of people in a community are vaccinated, the pathogen has a hard time circulating because most of the people it encounters are immune. In this way, the body is trained to fight the specific disease-causing organism, building up memory against the pathogen so it can fight it in the future. This is sometimes needed to allow for the production of long-lived antibodies and development of memory cells. Some vaccines require multiple doses, given weeks or months apart. This weakened version will not cause the disease in the person receiving the vaccine, but it will prompt their immune system to respond. In general, vaccines contain weakened or inactive parts of a particular organism that triggers an immune response within the body. A vaccine is intended to provide immunity against COVID-19.
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